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Showing posts with the label cancer of unknown primary

Cancer Diary: 🧠 Carl’s Story: Hypercalcemia in Real Life

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  For Carl, hypercalcemia didn’t just show up in lab results—it appeared as brain fog, confusion, and instability . He fell several times, a common outcome when calcium disrupts muscle and nerve function. These symptoms led him to the ER repeatedly, where doctors gave him IV infusions to quickly lower calcium levels. 💉 What’s in the ER Shots or Infusions? According to clinical guidelines, ER treatment for hypercalcemia of malignancy typically includes: IV fluids (saline) : The first step, flushing calcium through the kidneys. Bisphosphonates (pamidronate, zoledronic acid) : IV drugs that block bone breakdown and reduce calcium release. Denosumab : A targeted antibody used when bisphosphonates aren’t enough. Calcitonin injections : Fast-acting hormone therapy that lowers calcium within hours, though only short-term. Steroids : Sometimes used in lymphoma-related hypercalcemia. Dialysis : Reserved for severe cases with kidney failure. Carl received IV bisphosphonates/deno...

Cancer Diary: Implicit in Their Actions

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  When Carl was diagnosed with cancer of unknown primary (CUP), we didn't know yet what that meant. We had never heard of it before. Even after we learned more, we still clung to hope—because that’s what the doctors appeared to be offering. But their actions told a different story. CUP is brutal. It's rare and aggressive, and statistically, not many people survive it. The median survival rate hovers around 6 to 12 months. Fewer than 20% of patients live longer than a year. And Carl didn’t have just one form of cancer—he had five types present. They still couldn’t tell where the cancer began. Now, looking back, I understand what the oncologist must have seen in those test results. I also understand why they still tried to sound hopeful. The treatment plans were delivered with upbeat tones: targeted therapies, potential clinical trials, aggressive chemo. But there were moments—small, seemingly innocuous moments—when the mask of optimism slipped. One doctor handed Carl an advance ...

Cancer Diary: Memorial Day Reflections - Remembering, Honoring, and Embracing Life

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  Memorial Day is more than a holiday for me—it’s a deeply personal day of remembrance, reflection, and gratitude. It holds significance for me in three ways, each carrying its own weight of emotion and meaning. First, as a veteran who served during the Vietnam Conflict, I take this day to honor those I knew—those who fought, those who sacrificed, and those whose lives were forever altered by their service. Some of my military friends never returned home, and others carried the burdens of war long after leaving the battlefield. Today, I remember them. Memorial Day, traditionally observed by visiting cemeteries, is an opportunity for all of us to pause and recognize their courage. That brings me to Carl. His grave is another stop I will make today—not for military service, but because he, too, was taken far too soon. Cancer of Unknown Primary was his battle, and although his illness wasn’t linked to war, I can’t help but think of the veterans—especially those who served during Vie...

Cancer Diary: Resources for Veterans

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  This being Veterans Day, it seemed like a good research question to find out what resources exist for vets with cancer. Here is the answer: 1. VA National Oncology Program (NOP) The VA NOP provides comprehensive cancer care for veterans, including diagnosis, treatment, and survivorship support. They offer various services such as precision oncology, teleoncology, and clinical trials 2 . 2. CancerCare CancerCare offers support services for veterans, including financial assistance, counseling, and support groups. They also provide information on health care services and resources tailored for veterans 1 . 3. American Cancer Society The American Cancer Society provides resources specifically for veterans, including information on cancer risks, health care services, support groups, and financial assistance. They also offer a 24/7 helpline for cancer-related questions and support 3 . 4. Disabled American Veterans (DAV) DAV helps veterans connect with health care, disability, employmen...