MSI Press Blog

  🦴 How Bone Cancer Triggers Hypercalcemia Hypercalcemia in cancer is often caused by bone metastases —when cancer cells invade bone tissue and stimulate osteoclasts , the cells that break down bone. This breakdown releases calcium stored in the bones into the blood. The more aggressive or widespread the bone involvement, the higher the risk. There are two main pathways: Direct bone destruction : Seen in cancers like multiple myeloma, breast, lung, and prostate cancer that metastasize to bone. Paraneoplastic hormone production : Some tumors produce parathyroid hormone–related peptide (PTHrP) or excess calcitriol (vitamin D) , which also increase calcium levels. 🧬 Cancers Most Likely to Cause Hypercalcemia via Bone Involvement Multiple myeloma : Directly affects bone marrow and causes extensive bone breakdown. Breast cancer : Frequently metastasizes to bone. Lung cancer : Can cause hypercalcemia through both bone metastases and PTHrP production. Prostate cancer : Often...

  Hypercalcemia is a serious but treatable complication of cancer. It occurs when calcium levels in the blood rise too high, often signaling advanced disease. Recognizing its symptoms and understanding its causes can help patients and caregivers respond quickly. 🩺 What is Hypercalcemia? Hypercalcemia means higher-than-normal calcium levels in the blood . Calcium is essential for strong bones, muscle movement, nerve signaling, and heart rhythm. But when levels climb too high, the body’s systems are disrupted, leading to dangerous complications. 🎯 Which Cancers Are Linked to Hypercalcemia? Hypercalcemia is most often seen in advanced cancers . The cancers most commonly associated include: Breast cancer Bone cancer Lung cancer Kidney cancer Prostate cancer Multiple myeloma Leukemia and lymphoma Head and neck cancers Gastrointestinal cancers 🔬 How Does It Happen? Cancer can cause hypercalcemia through several mechanisms: Bone metastases : Tumors spread to bone, re...

  from treatment and recovery systems Many of the decisions that that Carl made in the last few months of his cancer-riddled life were completely irrational. In some cases, I did not know enough about the situations to know that they were irrational; they did not seem right, but the contractors went along with Carl. After all, he was paying, so it was his decision even if irrational.  Examples?  He had the sump pump behind the house removed and the area filled with concrete. During the first tremendous rains -- California's 2023 crazy storm season -- we ended up with a backyard swimming pool. The plumber reinstalled the sump pump.  He set up three generators (one probably would have done) powered by a wind turbine (we do have a lot of wind here) to maintain electricity if the power went out for a long period of time. Yes, we are on top of an earthquake fault, but we had not lost power for more than a couple of hours -- ever. And have not lost it at all since. To powe...

  Carl , who died from cancer August 16, 2021 would love to see me wearing my non-slid slipper sox . He was constantly slipping as he tried to walk with his walker, unbalanced from hypercalcemia. He found these sox online; they are stronger than the typical non-slid sox (click the link above to get to the sales site), warm, form-fitting, and comfortable.  I was always slipping when I tried to pull him up from his chair after he became too weak to stand on his own. I was barely strong enough to lift his 275-pound body with some help from him, and having sox skid me along the floor because his weight was more than my bicep strength created a dangerous situation. So, he ordered me several pairs, which came just as he was dying. I never got to wear them. He was in a Hoyer lift for transportation at that time. After he died, though the need for super-floor-sticking no longer existed, I cleaned his drawer and gave his sox (too big for me) to my son and daughter, whom they fit. Out o...