MSI Press Blog

  Today's post is short -- just a link -- but it could be more important than much longer posts. I recently came across the National Comprehensive Cancer Network and its compendium of drugs. Like Carl's Cancer Compendium, this collection of searchable and readily available information is a goldmine that I wish I had had when Carl was dying from cancer. You can check out this rich complication of cancer drugs and information about them HERE .  See other posts on cancer drugs . See other   Cancer Diary   posts. Blog editor's note: As a memorial to  Carl Don Leaver , co-founder of MSI Press LLC, and simply because it is truly needed, MSI Press is now hosting a web page,  Carl's Cancer Compendium , as a one-stop starting point for all things cancer, to make it easier for those with cancer to find answers to questions that can otherwise take hours to track down on the Internet and/or from professionals. The web page is in its infancy but expected to expand...

  Cancer is no longer a single story of despair. It’s a mosaic of progress — some cancers whisper and linger, others roar and demand urgent care. Across the board, survival is improving, and living well with cancer is increasingly possible. 🌍 Do We Have Cures? Yes, for some cancers. Childhood leukemias, testicular cancer, and Hodgkin lymphoma often reach long‑term remission rates above 90%. Early‑stage cervical and skin cancers can be cured surgically. Localized breast and prostate cancers are frequently treated successfully. For most others, medicine aims for control and remission — treating cancer as a chronic condition rather than a death sentence. ⚠️ Three Most Deadly Cancers Lung Cancer Often found late and spreads quickly. Living with it means managing fatigue, breathlessness, and emotional strain. Treated with surgery if localized, plus chemotherapy, targeted drugs, and immunotherapy. Average 5‑year survival: about 25%. Pancreatic Cancer Silent early phase; aggressive once ...

  You always hear about Stage 4 cancer...the scary stuff. Sometimes Stage 3. Rarely the other stages of cancer . Stage 4 is when we learned about Carl 's Cancer of Unknown Primary ; we hoped...while there really was no hope. What about Stage 1, though? Our neighbor just learned of a Stage 1 diagnosis, and her first response is to run away, ignore it, and, alternatively, to panic and tremble. So, I asked AI how should she respond? Here is what I got in response: While it's definitely concerning, stage 1 cancer is considered early-stage and highly treatable . The prognosis is generally very good, and many people go on to live healthy lives after treatment. Treatment options for stage 1 cancer typically include: Surgery : This is often the first line of treatment to remove the tumor. Depending on the type of cancer, a lumpectomy (removal of the tumor) or a more extensive surgery might be recommended. Radiation Therapy : This may be used after surgery to eliminate any remaining ca...

A new study from the Memorial Sloan Kettering Cancer Center has revealed a major side effect of the oral medication alpelisib that is prescribed to  breast cancer patients . Read about what the findings were HERE . Sheesh! It is so disappointing -- and frustrating -- to have to deal with the side-effects of the only drugs that can save your life. We went through that a little with Carl's Cancer of Uknown Primary. He did not last long enough to have many side effects. But many, many people do! Fingers crossed for new drugs that are free of bad side effects. For other Cancer Diary posts, click  HERE . Blog editor's note: As a memorial to Carl, and simply because it is truly needed, MSI Press is now hosting a web page,  Carl's Cancer Compendium , as a one-stop starting point for all things cancer, to make it easier for those with cancer to find answers to questions that can otherwise take hours to track down on the Internet and/or from professionals. The CCC is expanded and ...

  Carl, whose experience launched this blog and the MSI Press's Carl's Cancer Compendium (CCC) died after a very short 5 months post-diagnosis of occult cancer, or, as the official term goes, Cancer of Unknown Primary (CUP).  Carl fell February 23 and went to the local hospital where staff found advanced stage 4 metastatic cancer in five organs and subsequently transferred him to Stanford University Hospital, stating he would not likely return him. He did return home, for a brief four months--and he died at home on hospice almost a month later, having spent only 10 days in that capacity.  Stanford spent almost a month trying to determine the original cancer that had spread to these five organs (none of these organs was the original.) That is the problem with CUP. Finding the original seems out of reach and a guessing game. The doctor made his best guess, based on the spread pattern, but the cocktail he came up with for chemotherapy while doing no harm also did no good. T...

  For Carl, hypercalcemia didn’t just show up in lab results—it appeared as brain fog, confusion, and instability . He fell several times, a common outcome when calcium disrupts muscle and nerve function. These symptoms led him to the ER repeatedly, where doctors gave him IV infusions to quickly lower calcium levels. 💉 What’s in the ER Shots or Infusions? According to clinical guidelines, ER treatment for hypercalcemia of malignancy typically includes: IV fluids (saline) : The first step, flushing calcium through the kidneys. Bisphosphonates (pamidronate, zoledronic acid) : IV drugs that block bone breakdown and reduce calcium release. Denosumab : A targeted antibody used when bisphosphonates aren’t enough. Calcitonin injections : Fast-acting hormone therapy that lowers calcium within hours, though only short-term. Steroids : Sometimes used in lymphoma-related hypercalcemia. Dialysis : Reserved for severe cases with kidney failure. Carl received IV bisphosphonates/deno...