MSI Press Blog

  Cancer Diary: The Quiet Cancer There’s been a surge of interest lately in prostate cancer, due in part to the news about President Joe Biden’s health. I don’t know much about the specifics of his case, but the topic itself is an important one—and very often a quietly handled one, sometimes too quietly. Years ago, our parish priest confided in me—somewhat accidentally—that he had prostate cancer. What struck me most wasn’t the diagnosis, but the emotion attached to it: he was embarrassed . He didn’t want the congregation to know. I suppose he feared it was too private, too bodily, or too undignified to talk about. But I urged him to tell people. Not only did they have a right to know, they would want to know. They’d want to support him. He ended up doing just that. And I think, in the end, he was glad he did. People came out of the woodwork—not only to offer encouragement, but to share their own stories of prostate cancer and survival. Two parishioners even volunteered to drive h...

  Scientists at Nottingham Trent University have identified how a specific substance (a mutant) plays a key role in helping   prostate cancer   to spread and become harder to treat.  They hope the findings might offer new treatment options for aggressive prostate cancer. Read the full article HERE . For other Cancer Diary posts, click  HERE . Blog editor's note: As a memorial to Carl, and simply because it is truly needed, MSI Press is now hosting a web page,  Carl's Cancer Compendium , as a one-stop starting point for all things cancer, to make it easier for those with cancer to find answers to questions that can otherwise take hours to track down on the Internet and/or from professionals. The CCC is expanded and updated weekly. As part of this effort, each week, on Monday, this blog will carry an informative, cancer-related story -- and be open to guest posts:  Cancer Diary .   Sign up for the MSI Press LLC newsletter  here  or on our...

  🦴 How Bone Cancer Triggers Hypercalcemia Hypercalcemia in cancer is often caused by bone metastases —when cancer cells invade bone tissue and stimulate osteoclasts , the cells that break down bone. This breakdown releases calcium stored in the bones into the blood. The more aggressive or widespread the bone involvement, the higher the risk. There are two main pathways: Direct bone destruction : Seen in cancers like multiple myeloma, breast, lung, and prostate cancer that metastasize to bone. Paraneoplastic hormone production : Some tumors produce parathyroid hormone–related peptide (PTHrP) or excess calcitriol (vitamin D) , which also increase calcium levels. 🧬 Cancers Most Likely to Cause Hypercalcemia via Bone Involvement Multiple myeloma : Directly affects bone marrow and causes extensive bone breakdown. Breast cancer : Frequently metastasizes to bone. Lung cancer : Can cause hypercalcemia through both bone metastases and PTHrP production. Prostate cancer : Often...

  By the time, Carl was diagnosed, his cancer was metastized to his liver, lungs, bones, and upper stomach. After many biopsies and scans, the primary could not be found, and the cancer was officially labeled Cancer of Unknown Primary . Impaired Mobility: harder and harder to walk and climb stairs     We associated this with worsening of gout, which had been present for more than a decade     This could have been due as well to cancer-related hypercalcemia and bone cancer Frequent urination     We associated this with normal aging     This could have been related to  prostate cancer (not the case with Carl but the case with many) Pain in the side     We associated this with a gallbladder attack; it appeared similar to what our daughter, who had her gallbladder removed, had gone through.     We did not know that this same kind of pain is diagnostic of liver cancer. Frequent dozing off while working on the com...

  Carl did not like to walk. That was not the only thing that did him in, but it was one of the things that might have helped him. The benefits of walking can be immense: Walking increases muscular strength , especially lean muscle mass and functional strength. Walking a mile a day has been found to lower the risk of dying from breast cancer and prostate cancer . In addition, walking and  aerobic exercise diminishes the side effects of cancer and cancer treatment , such as fatigue, anxiety and depression. See also  Walking for Exercise | Cancer Today (cancertodaymag.org) . Walking can improve mental health , thanks to releasing endorphins. Walking can decrease the likelihood of diabetes . Walking can decrease bad cholesterol . Walking can decrease high blood pressure . Walking can reduce cardiovascular risk by 14%. Finally, walking a mile a day can cut risk of dying from prostate or breast cancer by 40% says one study .  For another MSI Press blog post on walking...

  Who would have thunk? There appears to be a link between skin cancer and acne. Well, every bit of forewarning helps -- especially in reminding all of us, not just those who suffer from acne, to wear sunscreen and not to lie around for hours tanning in the sun. If we weren't born with brown skin, well, that's life. Browning it in youth and risking skin cancer later is so not worth it! Take a look at the research HERE . It's not just the obvious skin cancer that acne might predict, it is also other kinds of cancers, like breast cancer, ovarian cancer, prostate cancer, and some lymphomas.  And to muddy the waters, it could be that the propensity for skin cancer could be the reason for the acne. Shades of Schroedinger's cat -- or the old dilemma:: chicken or egg? For other Cancer Diary posts, click  HERE . Blog editor's note: As a memorial to Carl, and simply because it is truly needed, MSI Press is now hosting a web page,  Carl's Cancer Compendium , as a one-stop...