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Sleep Disruption and Circadian Rhythm Imbalance

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  Sleep is the body’s nightly act of repair — a rhythm that synchronizes mind, hormones, and mood. When that rhythm falters, the entire emotional system begins to wobble. Depression often hides in the spaces between wakefulness and rest, where the body’s clock loses its steady beat. What It Is Circadian rhythms are the internal cycles that govern sleep, appetite, temperature, and energy. They rely on light cues, consistent routines, and hormonal timing. When these rhythms are disrupted — by insomnia, irregular schedules, or nighttime screen exposure — the brain’s chemistry drifts out of sync. Melatonin, cortisol, and serotonin lose their coordinated dance. How It Contributes to Depression Sleep disruption doesn’t just cause fatigue; it alters the architecture of emotional regulation. The prefrontal cortex, which helps manage mood and decision-making, becomes less active. The amygdala, which processes threat and emotion, becomes more reactive. The result is a mind that feels both fo...